Applicator for continuous blood glucose measurement

ABSTRACT

The present disclosure relates to a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device is produced in a state in which a body attachment unit has been assembled inside an applicator, so as to minimize a user&#39;s additional work of attaching the body attachment unit to the body, thereby enabling the body attachment unit to be attached to the body only by simply activating the applicator. Particularly, the present invention provides a continuous blood glucose measurement device and an applicator, wherein the continuous blood glucose measurement device: includes a wireless communication chip in a body attachment unit so as to enable communication with an external terminal, thereby enabling simple and convenient use thereof, without additional work for connecting a separate transmitter, and easier maintenance; and is activated by a user&#39;s operation after the body attachment unit is attached to the body, so as to enable the operation start time to be adjusted to an appropriate time according to user&#39;s needs, and to enable the operation to start in a stabilized state so that blood glucose can be measured more accurately.

TECHNICAL FIELD

The present disclosure is related to an apparatus for continuouslymeasuring blood glucose and an applicator. In more detail, the presentdisclosure is related to an apparatus for continuous blood glucosemeasurement and an applicator in which, by manufacturing in a state thatthe body attachable unit is assembled in an applicator, the bodyattachable unit can be attached to a human body by simply operating theapplicator by minimizing additional work, specially, by including awireless communication chip in the body attachable unit in order toprovide telecommunication with an external terminal, it is possible thatthe use can be more simple and convenient without additional work forconnecting a separate transmitter and the maintenance can also be moreeasily performed, and by initiating the operation according to themanipulation of the user after the body attachable unit is attached tothe human body, the operation start time can be adjusted to a propertime depending on the need of the user, the operation can be started ina stable status and more precise blood glucose measurement can beprovided.

BACKGROUND

Diabetes is a chronic medical condition that is common in modern people,and in the Republic of Korea, there are 2 million diabetes patients,about 5% of the total population.

Diabetes occurs when the absolute level of the sugar level in blood ishigh due to the absolute deficiency or relative insufficiency ofinsulin, produced by the pancreas, caused by various reasons such asobesity, stress, poor eating habits, and inherited hereditary factorsand imbalance regarding glucose in the blood.

The blood usually contains a certain concentration of glucose, andtissue cells gain energy from the glucose.

However, when the glucose is increased excessively more than needed, theglucose cannot be properly stored in the liver, muscle, or adiposetissue and is accumulated in the blood, because of this, patients withdiabetes maintain a much higher blood glucose level than normal people,and as excessive blood glucose passes through the tissues and isdischarged into the urine, it results in deficiency of glucose, which isabsolutely necessary for all tissues of the body, thereby causingabnormalities in respective body tissues.

Diabetes is characterized by substantial absence of subjective symptomsat the beginning of the condition, when diabetes progresses,diabetes-specific symptoms such as overdrink, overeat, polyuria, weightloss, weariness, skin itchiness, and lower ability of naturally healingon injury on hands and feet are shown, and further progression ofdiabetes leads to complications such as visual disturbances,hypertension, kidney disease, paralysis, periodontal disease, musclespasms and neuralgia, as well as gangrene.

In order to diagnose diabetes beforehand and manage to prevent theprogression of diabetes into complications associated therewith,systematic blood glucose measurement and treatment should be performed.

For diabetes patients as well as people having higher than normal bloodglucose, even though diabetes has not yet developed, medical devicemanufacturers offer a variety of blood glucose meters to measure bloodglucose levels at home.

Glucose measuring devices may be categorized into a single timemeasurement type measuring a blood glucose level and collecting bloodfrom a fingertip by a user every single time and a continuousmeasurement type attaching a glucose monitoring system to the belly oran arm of the user and continuously measuring blood glucose levels.

Diabetics patients generally experience hyperglycemia and hypoglycemia,an emergency may occur in the hypoglycemic conditions, and the patientsmay become unconscious or die if a hypoglycemic condition lasts for anextended period of time without the supply of sugar. Accordingly,although rapid discovery of the hypoglycemic condition is criticallyimportant for diabetics, blood-collecting type glucose monitoringdevices intermittently measuring glucose have limited ability toaccurately measure blood glucose levels.

Recently, to overcome such a drawback, continuous glucose monitoringsystems (CGMSs) inserted into the human body to measure a blood glucoselevel every few minutes have been developed, and therefore easilyperform the management of diabetics and responses to an emergencysituation.

Additionally, the blood-collecting glucose monitoring system performsthe glucose measurement by collecting blood by pricking a pain-sensitivefingertip with a needle by the diabetes patients themselves, andtherefore, the blood collecting process may cause pain and aversion. Tominimize such pain and aversion, research and development regarding theCGMSs, which can continuously measure glucose levels by inserting aneedle-shaped sensor into a portion of the human body, such as the bellyor an arm, which is less pain sensitive, have been undertaken, andfurthermore, research and development of non-invasive glucose monitoringsystems for measuring glucose without collecting blood have beenactively undertaken.

Over the past 40 years, non-invasive glucose monitoring systems havebeen studied regarding various methods of measuring glucose withoutcollecting blood, for example, optical methods, electrical methods,exhalation measurement methods, and the like. Cygnus Corporation, RedwooCity, Calif., U.S.A, has developed and launched the Glucowatch® G2Biographer, a wrist watch type, using reverse iontophoresis, but thesales of this product were stopped in 2007, because of many problems,such as skin stimulation issues and qualification approval issues,malfunction caused by sweating, and low reliability in measurement ofhypoglycemia comparing with hyperglycemia. Although a variety ofnon-invasive glucose monitoring techniques have been introduced andreported to date, there have been no practical uses due to lowreliability or accuracy.

A continuous glucose monitoring system includes a sensor module attachedto the skin of the human body and measuring a blood glucose level byextracting body fluid, a transmitter transmitting the blood glucoselevel measured by the sensor module to a terminal, the terminaloutputting the received blood glucose level, and any other appropriatecomponent. The sensor module includes a needle-shaped sensor probe forinsertion into subcutaneous fat to extract interstitial fluid and anyother appropriate component. A separate applicator for attaching thesensor module to the body is used.

Those continuous glucose monitoring systems are manufactured to have awide variety of types depending on their manufacturers, and are used ina variety of methods. However, the most of the continuous glucosemonitoring systems are manufactured and distributed as a type that aone-time use sensor module is attached to the human body using anapplicator, the user should perform multistage operations/manipulationto operate the applicator to attach the one-time use sensor module tothe human body, and after the sensor module is attached to the humanbody, the user should perform various follow-up operations, such as aprocedure of withdrawing a needle by the user.

For example, many operations of unpacking the one-time use sensormodule, accurately inserting the one-time use sensor module into theapplicator, operating the applicator and inserting the sensor moduleinto the skin in a state that the sensor module is inserted to theapplicator, after the insertion, withdrawing the needle of the sensormodule from the skin using a separate device, and so on should beperformed, and in order to transmit the measurement results regardingglucose to a user terminal, the operation of connecting a separatetransmitter to the sensor module and any other appropriate operationshould be performed.

Accordingly, the operations of measuring glucose using the continuousglucose monitoring systems may be significantly difficult andinconvenient, which are problematic. Additionally, because theoperations of the sensor module and the transmitter is not initiated bythe user, there may be problems, for example, low accuracy of the bloodglucose measurement result and short device lifespan.

SUMMARY Technical Problem

The present disclosure is invented to solve problems in conventionaltechnique, and the purpose of the present disclosure is for providing anapparatus for continuous blood glucose measurement and an applicator forcontinuous blood glucose measurement in which, by manufacturing in astate that the body attachable unit is assembled in an applicator, thebody attachable unit can be attached to a human body by simply operatingthe applicator by minimizing additional work, specially, by including awireless communication chip in the body attachable unit in order toprovide telecommunication with an external terminal, it is possible thatthe use can be more simple and convenient without additional work forconnecting a separate transmitter and the maintenance can also be moreeasily performed.

Another purpose of the present disclosure is for providing an apparatusfor continuous blood glucose measurement and an applicator in which, byinitiating the operation according to the manipulation of the user afterthe body attachable unit is attached to the human body, the operationstart time can be adjusted to a proper time depending on the need of theuser, and the operation can be started in a stable status and moreprecise blood glucose measurement can be provided.

Solution to Problem

According to an embodiment of the present disclosure, an applicator forcontinuous glucose measurement, the applicator, in which a bodyattachable unit is coupled, configured to outwardly discharge the bodyattachable unit by manipulation of a user to insertingly attach the bodyattachable unit to a body, may comprise a main case having an innerspace and an open side, wherein a pressure button is installed at oneside of the main case to be manipulated by the user; and a plunger bodydisposed in a first location inside the main case and configured to belinearly movable to a second location in an outward discharge directionaccording to manipulation of the pressure button, wherein the bodyattachable unit coupled to the plunger body is movable from the firstlocation to the second location together with the plunger body, thepressure button is installed to be mode-changeable between a safe mode,in which pressurizing movement by pressurizing manipulation isprevented, and a pressure standby mode, in which the pressurizingmovement by the pressurizing manipulation is allowed, and the pressurebutton comprises a locking unit configured to block a mode change fromthe safe mode to the pressure standby mode, and release from block ofthe mode change by the manipulation of the user.

In this embodiment, the locking unit may be configured that a state ofblocking the mode change and a state of releasing from the block of themode change are visually identifiable.

Additionally, the pressure button may be configured to be mode-changedfrom the safe mode to the pressure standby mode by being slidably movedalong an outer surface of the main case, and the locking unit may beconfigured to block the mode change of the pressure button by limitingsliding movement of the pressure button.

Further, the main case may comprise: an outer case comprising a buttonguide groove slidably movably coupled with the pressure button andformed at one side of the outer case; and an inner case coupled to aninside of the outer case, the inner case configured to guide a linearmovement path of the plunger body, one end of the locking unit may becoupled to the pressure button and an other end of the locking unit maybe interlocked with the button guide groove to limit the slidingmovement of the pressure button.

Additionally, the locking unit may comprise: a locking main body ofwhich one end is coupled to the pressure button to be manipulated by theuser, and a locking hook protruding at one side of the locking main bodyto be interlocked with an inner circumferential surface of the buttonguide groove.

Further, the locking main body of the locking unit may be rotatablycoupled to the pressure button, and an interlocking state of the lockinghook may be released according to the user's rotating manipulation ofthe locking main body.

Additionally, the locking main body of the locking unit may beconfigured to be elastically transformable, and an interlocking state ofthe locking hook may be released according to the manipulation of theuser which elastically transforms the locking main body.

Further, the locking main body of the locking unit may be configured tobe separable and removable from the pressure button, and an interlockingstate of the locking hook may be released according to the manipulationof the user which separates and removes the locking main body.

Advantageous Effects of Invention

According to an embodiment of the present disclosure, by manufacturingin a state that the body attachable unit is assembled in an applicator,the body attachable unit can be attached to a human body by simplyoperating the applicator by minimizing additional work, specially, byincluding a wireless communication chip in the body attachable unit inorder to provide telecommunication with an external terminal, it ispossible that the use can be more simple and convenient withoutadditional work for connecting a separate transmitter and themaintenance can also be more easily performed.

Additionally, by initiating the operation according to the manipulationof the user after the body attachable unit is attached to the humanbody, the operation start time can be adjusted to a proper timedepending on the need of the user, and the operation can be started in astable status and more precise blood glucose measurement can beprovided.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a perspective view of schematically illustrating an outerstructure of a continuous blood glucose measurement apparatus accordingto an embodiment of the present disclosure,

FIG. 2 is a perspective view of schematically illustrating an outerstructure of a body attachable unit according to an embodiment of thepresent disclosure,

FIG. 3 is an exploded perspective view of the continuous blood glucosemeasurement apparatus according to an embodiment of the presentdisclosure,

FIG. 4 is a cross-section view taken along line “B-B” of FIG. 1,

FIG. 5 is a cross-section view taken along line “A-A” of FIG. 1,

FIG. 6 is an exploded perspective view of schematically illustratingconfiguration of a protection cap according to an embodiment of thepresent disclosure,

FIGS. 7 and 8 are views of illustrating operations for removing andseparating a release paper as well as a protection cap according to anembodiment of the present disclosure.

FIG. 9 is a perspective view of schematically illustrating a couplingstructure of a pressure button according to an embodiment of the presentdisclosure,

FIGS. 10 and 11 are views of schematically illustrating mode changestructures of a pressure button according to an embodiment of thepresent disclosure,

FIG. 12 is a view of schematically illustrating a pressurizing operationstate of a pressure button according to an embodiment of the presentdisclosure,

FIGS. 13 and 14 are perspective views of schematically illustratingmovement states of a shooting plate caused by operations of a pressurebutton unit according to an embodiment of the present disclosure,

FIGS. 15 and 16 are views illustrating separation structures of anapplicator and a body attachable unit according to an embodiment of thepresent disclosure,

FIGS. 17 to 19 are views illustrating structures for preventing reuse ofan applicator according to an embodiment of the present disclosure,

FIG. 20 is a view illustrating an operation structure of needleextracting means according to an embodiment of the present disclosure,

FIGS. 21 to 25 are views illustrating use states of a continuous bloodglucose measurement apparatus according to operation order step by stepaccording to an embodiment of the present disclosure,

FIG. 26 is a perspective view conceptually illustrating an outerstructure of a body attachable unit attached to a human body accordingto an embodiment of the present disclosure,

FIG. 27 is an exploded perspective view conceptually illustratingcomponents of a body attachable unit,

FIG. 28 is a cross-sectional view taken along line “C-C” of FIG. 26,

FIG. 29 is a cross-sectional view taken along line “D-D” of FIG. 26,

FIG. 30 is a conceptual view illustrating a operation state of apressurizing operation module according to an embodiment of the presentdisclosure,

FIG. 31 is a perspective view of schematically illustrating detailedconfiguration of a pressurizing operation module according to anembodiment of the present disclosure,

FIG. 32 is a perspective view of schematically illustrating detailedconfiguration of a sensor unit according to an embodiment of the presentdisclosure,

FIG. 33 is a view of conceptually illustrating a pressurizing operationstate of a sensor unit according to an embodiment of the presentdisclosure,

FIG. 34 is a view of conceptually illustrating arrangement relationbetween a sensor unit and an electrical contact point according to anembodiment of the present disclosure,

FIGS. 35 to 37 are views of conceptually illustrating variousconfigurations of electrical contact points according to embodiments ofthe present disclosure,

FIGS. 38 and 39 are views schematically illustrating a structure of amode change locking unit of a pressure button according to an embodimentof the present disclosure,

FIGS. 40 and 41 are views schematically illustrate a structure andoperation status of a pressurizing operation module according to anotherembodiment of the present disclosure,

FIG. 42 is a view schematically illustrate a structure of a pressurizingoperation module according to still another embodiment of the presentdisclosure,

FIG. 43 is a perspective view of schematically illustrating detailedconfiguration of a sensor unit according to still another embodiment ofthe present disclosure,

FIG. 44 is a perspective view of a structure of a pressure transformingunit of a sensor unit according to an embodiment of the presentdisclosure,

FIG. 45 is a view of showing various alternative examples of a sensorunit according to embodiments of the present disclosure,

FIG. 46 is a cross-section view taken along line “E-E” of FIG. 45 forillustrating an electrode layer-built structure of a sensor unitaccording to an embodiment of the present disclosure, and

FIGS. 47 and 48 are cross-section views taken along line “E-E” of FIG.45 for illustrating electrode layer-built structures of a sensor unitaccording to other embodiments of the present disclosure.

DETAILED DESCRIPTION OF EMBODIMENTS

Hereinafter, embodiments of the present disclosure will be described indetail with reference to the accompanying drawings. Throughout thisdocument, reference should be made to the drawings, in which the samereference numerals and symbols will be used to designate the same orlike components. Additionally, in the following description of thepresent disclosure, detailed descriptions of known functions andcomponents incorporated herein will be omitted in the case that thesubject matter of the present disclosure may be rendered unclearthereby.

FIG. 1 is a perspective view schematically illustrating an outerstructure of a continuous blood glucose measurement apparatus accordingto an embodiment of the present disclosure, and FIG. 2 is a perspectiveview schematically illustrating an outer structure of a body attachableunit according to an embodiment of the present disclosure, FIG. 3 is anexploded perspective view of the continuous blood glucose measurementapparatus according to an embodiment of the present disclosure, FIG. 4is a cross-section view taken along line “B-B” of FIG. 1, and FIG. 5 isa cross-section view taken along line “A-A” of FIG. 1.

According to an embodiment of the present disclosure, a continuous bloodglucose measurement apparatus may be manufactured as one single unitproduct that a body attachable unit (20) is assembled inside anapplicator (10), and has a simpler structure which can be easily used byminimizing additional work of a user when using the continuous bloodglucose measurement apparatus.

The body attachable unit (20) may be configured to be attachable to ahuman body to periodically measure blood sugar level or glucose byextracting body fluid, and transmit the blood glucose measurement resultto an external device such as an external terminal (not shown) and soon. A sensor unit (520) of which one end portion can be inserted intothe human body and a wireless communication chip (540) (see FIG. 27)configured to wirelessly communicate with the external terminal can bedisposed inside the body attachable unit (20), and therefore, the bodyattachable unit (20) can be used without additional connection of aseparate transmitter.

The applicator (10) is formed such that the body attachable unit (20) isfixedly coupled to inside of the applicator (10), and the applicator(10) is configured to outwardly discharge the body attachable unit (20)according to the manipulation of the user.

In this embodiment, the body attachable unit (20) is assembled andproduced in a state that the body attachable unit (20) is inserted intothe inside of the applicator (10), and is configured to move in anoutward discharge direction pursuant to the operation of the applicator(10) by the manipulation of the user and be attached to the human body.

Therefore, the sensor applicator assembly (1) according to an embodimentof the present disclosure is assembled and manufactured in a state thatthe body attachable unit (20) is inserted in the inside of theapplicator (10) at the manufacturing stage and the body attachable unit(20) can be attached to a skin by only the operation of the applicator(10), and because the sensor applicator assembly (1) is suppled to theuser in this state, the user can easily attach the body attachable unit(20) to the skin by only the manipulation simply activating theapplicator (10) without extra additional operation for attaching thebody attachable unit (20) to the skin. Specifically, since the bodyattachable unit (20) has the wireless communication chip (540), noconnection with an extra transmitter is needed and therefore it can beused more conveniently.

In a conventional continuous blood glucose measurement apparatus, afterremoving a body attachable unit, which is separately packaged, preciselyinserting it into an applicator, and then operating the applicator, thebody attachable unit is attached to a skin, but the work preciselyinserting the body attachable unit into the applicator is cumbersome aswell as difficult and there is a problem in lowering the accuracy ofblood glucose measurement because of contaminating the body attachableunit when young children or elderly adults perform this procedure.

In an embodiment of the present disclosure, at the manufacturing stage,it is manufactured and distributed in a state that the body attachableunit (20) is inserted in the applicator (10), and therefore the stepthat the user removes the body attachable unit (20) from the package andinserts it into the applicator (10) may be omitted, because the bodyattachable unit (20) can be attached to the skin by simply manipulatingthe applicator (10), the usability may be significantly improved, andspecifically, the accuracy of blood glucose measurement may be improvedby preventing the contamination of the body attachable unit (20).

Since it is manufactured in a state that the body attachable unit (20)is inserted in the applicator (10), the body attachable unit (20) andthe applicator (10) can be preferably used one time only, not reusable.For this impossibility of the reusable structure, according to anembodiment of the present disclosure, the body attachable unit (2) isconfigured not to be re-insertable after the body attachable unit (20)inserted in the inside of the applicator (10) is externally discharged.

Therefore, the applicator (10) is formed to be open at one side and thebody attachable unit (20) is outwardly discharged through the open sideof the applicator (10) to the outside of the applicator (10), and if thebody attachable unit (20) is externally discharged by a first one timeoperation of the applicator (10), it is configured that the bodyattachable unit (20) cannot be inserted by the user so that another bodyattachable unit (20) cannot be inserted into the applicator (10) andused after that.

Meanwhile, a separate and additional protection cap (200) can beseparably coupled to the applicator (10) in order to block externalexposure in a state that the applicator (10) is inserted in the insideof the applicator (10), and it may be configured that the user canattach the body attachable unit (20) to the human body by operating theapplicator (10) only after the protection cap (200) is separated.

In the embodiment of the present disclosure, an adhesive tape (560) isprovided at a side of the body attachable unit (20) contacting the humanbody to be attached to the body, to protect the adhesive tape (560) arelease paper (561) is attached to a surface of the adhesive tape (560)contacting the human body, and the release paper (561) of the adhesivetape (560) may be configured to be separated and removed from theadhesive tape (560) during the operation of separating the protectioncap (200) from the applicator (10).

For example, the release paper (561) may be configured to adhere oneside of the release paper (561) to the protection cap (200), andtherefore, if the user separates the protection cap (200) from theapplicator (10), the release paper (560) may be separated and removedfrom the adhesive tape (560) together with the protection cap (200).Accordingly, if the user separates the protection cap (200), the releasepaper (561) of the adhesive tape (560) is separated and removed, andtherefore in this status the body attachable unit (20) can be attachedto the human body by the operation of the applicator (10).

Additionally, in a state that the body attachable unit (20) is insertedin the inside, the applicator (10) fixes the body the attachable unit(20), and in a state that the body attachable unit (20) is outwardlydischarged and moved, the applicator (10) is configured to release thefixed state of the body attachable unit (20). Accordingly, in a statethat the body attachable unit (20) is assembled to be inserted in theinside of the applicator (10), the body attachable unit (20) maintainsthe fixed state, and when the body attachable unit (20) is externallydischarged and attached to the skin by actuating the applicator (10),the state fixed between the applicator (10) and the body attachable unit(20) is released, and therefore if the applicator (10) is separated inthis state the applicator (10) is separated from the body attachableunit (20) and only the body attachable unit (20) remains on the skin.

Meanwhile, the body attachable unit (20) according to an embodiment ofthe present disclosure is configured to cause the sensor unit (520) andthe wireless communication chip (540) to initiate their operationsthrough a separate switching means controlled by the user. Accordingly,after inserting and attaching the body attachable unit (20) to the humanbody by using the applicator (10), the user may initiate to operate thebody attachable unit (20) through the switching means or otherappropriate means included in the body attachable unit (20), and fromthe time of the initiation of the operation the sensor unit (520) andthe wireless communication chip (540) may be operated, the blood glucoseof the human body may be measured, and the measurement result may betransmitted to the external terminal. In this embodiment, the switchingmeans operated by the user may be implemented in various ways, and thedetailed description of such a switching means and the body attachableunit (20) will be described later with reference to FIGS. 26 to 37.

Additionally, in the body attachable unit (20), the sensor unit (520) isdisposed in a housing (510) which is formed to be capable of separatinginto an upper housing (512) and a lower housing (511), and one endportion of the sensor unit (520) outwardly protrudes from the housing(510) so that it can be inserted and attached to the human body. Thesensor unit (520) may comprise a sensor probe unit (521) to be insertedinto the human body, and a sensor body unit (522) disposed inside thehousing (510), and the sensor probe (521) and the sensor body unit (522)are formed as one end portion and another end portion of the sensor unit(520), respectively, and in a bent shape.

In this embodiment, to smoothly perform the body insertion process ofthe sensor unit (520), a separate needle unit (550) may be separatablycoupled to the housing (510). The needle unit (550) may surround one endportion of the sensor unit (520) and be configured to be insertedtogether with the sensor unit (520) so that one end portion of thesensor unit (520) can be stably inserted into the human body.

As shown in FIG. 2, the needle unit (550) may be separatably coupled tothe housing (510) in a direction penetrating the top and bottom of thehousing (510) of the body attachable unit (20), the needle unit (550)may be formed to have a structure covering the outside of the sensorunit (520), and a need head (551) is formed at the upper end portion ofthe needle unit (550). If the body attachable unit (20) is moved in thedirection outwardly discharged by the applicator (10), the needle unit(550) is inserted into the human body first before the sensor unit (520)is inserted into the human body and the needle unit (550) may supportthe sensor unit (520) such that the sensor unit (520) can be stablyinserted in the skin. The needle unit (550) may be coupled with a needleextracting body (400) of the applicator (10) through the needle head(551), and after the body attachable unit (20) is inserted and attachedto the human body by the operation of the applicator (10), the needleunit (550) may be configured to be withdrew and removed from the humanbody by the needle extracting body (400) of the applicator (10).

Next, the details of components of the applicator (10) according to anembodiment of the present disclosure will be followed.

The applicator (10) according to an embodiment of the present disclosuremay comprise a main case (100), wherein a pressure button (110)configured to perform pressure operation by the user is installed at oneside of the main case (100), a plunger body (300) coupled to a firstlocation of the inside of the main case (100) and configured to bedecoupled from the first location by the operation of the pressurebutton (110) and linearly move from the first location to a secondlocation in an outward discharge direction, and a plunger elastic spring(S1) configured to apply an elastic force to the plunger body (300) sothat the plunger body (300) can linearly move from the first locationand the second location, and the body attachable unit (20) is coupledwith one side of the plunger body (300) and the body attachable unit(20) is configured to be moved together with the plunger body (300) fromthe first location to the second location.

As discussed above, the protection cap (200) as a separate element maybe separatably coupled to the lower end portion of the main case (100)to protect the inside of the body attachable unit (20).

As illustrated in FIGS. 6 to 8, the protection cap (200) may comprise anouter side cover unit (201) covering and contacting an outercircumferential surface of the applicator (10) and formed to be coupledwith one end portion of the applicator (10), an extension unit (202)extending from one end of the outer side cover unit (201) in a directiontoward the inner center of the applicator (10), and an inner sidesupporting unit (203) upwardly extending from the extension unit (202)and configured to support a surface of the body attachable unit (20)contacting the human body inserted in the inside of the applicator (10).In this embodiment, at the center portion of the inner side supportingunit (203), the sensor protection unit (204) may be formed to partiallydownward-protrude to surround a sensor probe (521) downwardly protrudingfrom a surface of the body attachable unit (20) contacting the humanbody and the needle unit (550).

Accordingly, the protection cap (200) can block the outside exposure ofthe body attachable unit (20) inserted in the inside of the applicator(10) as well as perform the function of supporting the body attachableunit (20), and may improve the overall structural stability of theapplicator.

Meanwhile, as shown in FIGS. 7 and 8, the adhesive tape (560) and therelease paper (561) are attached to a surface of the body attachableunit (20) which is to be contacted with the human body, and the releasepaper (561) of the adhesive tape (560) is configured to be separated andremoved from the adhesive tape (560) together with the protection cap(200) in the process of separating the protection cap (200) from theapplicator (10).

In this embodiment, the release paper (560) may be applied to the uppersurface of the inner side supporting unit (203) of the protection cap(200), and may be attached to the inner side supporting unit (203) ofthe protection cap (200) through separate adhesive material (562).Accordingly, as illustrated in FIG. 7, the separate adhesive material(562) is adhered to one side of the lower surface of the release paper(561), and this adhesive material (562) is disposed between the uppersurface of the inner side supporting unit (203) of the protection cap(200) and the release paper (561) and the lower surface of the adhesivematerial (562) is adhered to the upper surface of the inner sidesupporting unit (203). The adhesive strength of the adhesive material(562) may be greater than the adhesive strength between the releasepaper (561) and the adhesive tape (560). Accordingly, if the protectioncap (200) is separated from the applicator (10), the release paper (561)adhered to the inner side supporting unit (203) of the protection cap(200) is also separated together with the protection cap (200) throughthe adhesive material (562) and separated and removed from the adhesivetape (560).

In this embodiment, at the release paper (561), two cutting lines (notshown) separated with a separation distance identical to a width of theadhesive material (562) are formed to be parallel to each other at somesections, and therefore, as illustrated in FIG. 8, in the process ofseparating the protection cap (200), the release paper (562) isseparated and removed away from the adhesive tape (560) along thecutting lines together with the adhesive material (562) first and thenas the separation operation of the protection cap (200) is beingperformed, i.e., the protection cap (200) keeps being downwardly movedwith reference to a direction shown in FIG. 8, a portion of the releasepaper (562) except the cutting lines is pulled and separated and removedfrom the adhesive tape (560). By this operation of separating andremoving the release paper, the separation-removal operation of therelease paper (561) may be smoothly and stably performed.

The pressure button (110) is installed at the main case (100) forpressure operation by the user, and a shooting plate (150) configured tobe movable according to the pressure operation of the pressure button(110) may be movably coupled to the inside of the main case (100).

The plunger body (300) may be configured to be coupled and interlockedwith the shooting plate (150) and fixed at the first location, and to bereleased from the interlock with the shooting plate (150) according tothe movement of the shooting plate (150) and be moved to the secondlocation by the elastic force of the plunger elastic spring (S1).

The main case (100) may comprise an outer case (101), wherein thepressure button (110) is installed to one side of the outer case (101),and an inner case (102) coupled at the inside of the outer case (101)and configured to guide a linear movement path of the plunger body(300), and the shooting plate (150) may be configured to be movablewhile being supported in the inner case (102).

The pressure button (110) is coupled to the outer case (101) in order tobe capable of performing the operation of applying pressure, and asshown in FIG. 9, a button guide groove (1011) is formed at the outercase (101) so that the pressure button (110) can be coupled in order tobe capable of performing the operation of applying pressure. Thepressure button (110) is configured to be capable of the pressureoperation by a structure that a portion of the pressure button (110) isconfigured to be rotatable around a hinge axis (112) formed at an upperend portion of the pressure button (110), a pressure rod (111) is formedat a lower end portion of the pressure button (110) to apply thepressure to the shooting plate (150), and a separate fixing hook (113)is formed at one side of the pressure button (110) to prevent separationand removal of the pressure button (110).

The pressure button (110) is installed to be configured to provide modechange between a safe mode blocking the pressure movement performedaccording to the pressure operation and a pressure standby mode capableof performing the pressure movement performed according to the pressureoperation.

The pressure button (11) may be configured to, in a safe mode state,slidingly move along an exterior surface of the main case (100) for acertain section to change to a standby mode state. A hanging raised part(1012) is formed at a portion of the main case (100) where the pressurebutton (110) is coupled, in the safe mode state, the pressure button(110) is interlocked with the hanging raised part (1012) to block thepressuring movement, and as the sliding movement is from the safe modestate to the pressure standby mode state performed, the interlock fromthe hanging raised part (1012) is released to make the pressuringmovement possible.

Accordingly, as illustrated in FIG. 10, in the safe mode state, thepressure button (110) is interlocked at the hanging raised part (1012)of the outer case (101) so that the pressurizing operation cannot beperformed, and as illustrated in FIG. 11, when the pressure button (110)is upwardly moved to the pressure standby mode state, the interlock withthe hanging raised part (1012) of the outer case (101) is released andit is possible to perform the pressurizing operation.

If the pressure button (110) in the safe mode state is slidingly movedto the pressure standby mode, the position of the pressure button (110)may be fixed not to return to the safe mode state.

For this, a fixing protrusion (114) is formed at one side of thepressure button (110), a transformable cut portion (1013) is formed atthe bottom surface of the button guide groove (1011) of the outer case(101) and in a structure that a certain section is cut to be elasticallytransformable, the transformable cut portion (1013) comprises areceivable groove (1014) configured to be insertedly receive the fixingprotrusion (114) when the pressure button (110) is positioned at thesafe mode, and in a state that the movement of the pressure button (110)to the pressure standby mode is completed, an end portion of thepressure button (110) is interlocked with the fixing protrusion (114) toblock the returning movement of the pressure button (110).

In such a structure, the pressure button (110) can perform pressurizingoperation by manipulated by the user only in a state that it isslidingly moved to the pressure standard mode state, and therefore thepressure operation caused by the user's mistake can be prevented and itis possible to use safely.

If the pressure button (110) is changed to the pressure standby modestate and the pressurizing operation is performed as shown in FIG. 12,the pressure button (110) the pressure rod (111) of the pressure button(110) applies pressure to and moves the shooting plate (150).

The shooting plate (150) is supported in the inner case (102) andslidably movably coupled according to the pressurizing operation of thepressure button (110), and the plunger body (300) is interlocked withthe shooting plate (150) at the first location and according to themovement of the shooting plate (150) the interlock with the shootingplate (150) is released and the plunger body (300) is moved to thesecond location by the elastic force of the plunger elastic spring (S1).

An interlock hook (310) is formed at the plunger body (300) to interlockwith the shooting plate (150) as illustrated in FIGS. 12 and 13, thehanging protrusion part (153) interlockable with the interlock hook(310) of the plunger body (300) is formed at one side of the shootingplate (150), and the hanging protrusion part (153) may be configured tobe released from the state interlocking with the interlock hook (310) asthe shooting plate (150) is slidingly moved.

At the inner case (102), the guide rail (162) is formed to protrude toguide the slide movement path of the shooting plate (150), and the guideslot (151) is formed at the shooting plate (150) to insertedly guide theguide rail (162). And, an elastic structure (163) elastically supportingthe shooting plate (150) in a direction opposite to a slide movementdirection by the operation of the pressure button (110) is installed atthe inner case (102). Accordingly, the shooting plate (150) iselastically supported by the pressure button (110) by the elastic forceof the elastic structure (163), and therefore unless the pressure button(110) is manipulated for pressurization, the interlocking status of theplunger body (300) with the interlock hook (310) can be stablymaintained.

According to such a structure, when the user operates to pressurize thepressure button (110), the shooting plate (150) is slidingly moved, andthis may result in releasing the interlocked state of the plunger body(300) and the shooting plate (150) and the plunger body (300) isoutwardly discharged from the first location to the second location asshown in FIGS. 15 and 16.

A stopper protrusion (320) may be formed at the plunger body (300) tolimit a range movable to the second location, and as the plunger body(300) is moved to the second location, the stopper protrusion (320) canlimit the movement of the plunger body (300) by a way of beinginterlocked with one side of the inner case (102). Accordingly, theplunger body (300) can be moved up to the second location by the stopperprotrusion (320), and the plunger body (300) cannot be outwardlydischarged from the main case (100) over that range. In this embodiment,at the inner case (102), the plunger body (300) is interlocked with thestopper protrusion (320) in a state that the plunger body (300) is movedto the second location and a stopper fixing unit (1021) may be formed tolimit the movement of the stopper protrusion (320).

Additionally, a sensor receiving unit (301) is formed at one end portionof the plunger body (300) so that the body attachable unit (20) isinsertedly received, and the body attachable unit (20) is insertedlyreceived by the sensor receiving unit (301) and linearly move togetherwith the plunger body (300) from the first location to the secondlocation. As the plunger body (300) and the body attachable unit (20)are linearly moved to the second location, the sensor probe (512) andthe needle unit (550) of the body attachable unit (20) are inserted intothe human body.

In this embodiment, a sensor fixing hook (330) fixedly coupling the bodyattachable unit (20) by being interlockedly coupled with the bodyattachable unit (20) inserted to the sensor receiving unit (301) isinstalled at an edge of the sensor receiving unit (301). An interlockcoupling groove (5112) is formed at both end portions of the bodyattachable unit (20) to be interlocked with the sensor fixing hook (330)in a state that the body attachable unit (20) is inserted into thesensor receiving unit (301).

The sensor fixing hook (330) is coupled elastically rotatable around arotary axis (331), in a state that the plunger body (300) is positionedat the first location as shown in FIG. 15 the sensor fixing hook (33) iselastically supported and pressurized in an inward direction so that thesensor fixing hook (330) is interlockedly coupled with the interlockcoupling groove (5112) of the body attachable unit (20), and in a statethat the plunger body (300) is positioned at the second location asillustrated in FIG. 16 the sensor fixing hook (330) is configured to bereleased from the interlock with the interlock coupling groove (5112) ofthe body attachable unit (20) in the operation of separating theapplicator (10) from the body attachable unit (20). The operation ofreleasing the sensor fixing hook (330) from the interlock with the bodyattachable unit (20) can be performed in a way that the rotary shaft(331) twistingly and elastically rotates.

Although not illustrated, a hook guide unit (not shown) is formed on theinner surface of the inner case (102) and the hook guide unitpressurizes the sensor fixing hook (330) in an inward direction to beinterlocked with the body attachable unit (20) and has a cross-sectionalshape having a structure that the sensor fixing hook (330) is releasedfrom the pressurization in the state of the plunger body (300) moved tothe second location. Therefore, the hook guide unit may have a structurewith convex and concave surfaces on the inner surface of the inner case(102), the convex surface applies pressure to the sensor fixing hook(330) and the concave surface releases the sensor fixing hook (330) fromthe pressure application, and the concave is formed to release thesensor fixing hook (330) from the pressure application in a state thatthe sensor fixing hook (330) is moved together with the plunger body(300) to the second location.

Meanwhile, because the embodiment of the present disclosure ismanufactured in a state that the body attachable unit (20) is insertedin the applicator (10), the reuse of the body attachable unit (20) byinserting again another body attachable unit (20) to the applicator (10)may be prevented as described above.

For this purpose, the main case (100) includes return prevention meansfor preventing the plunger body (300) returning to the first locationafter the plunger body (300) is moved to the second location.

As illustrated in FIGS. 17 to 19, the return prevention means may beconfigured to comprise a interlocking body (340) formed on one side ofthe plunger body (300), and a return prevention hook (161) formed at theinner case (102) and configured to prevent the returning movement of theplunger body (300) by being interlockedly coupled with the interlockingbody (340) of the plunger body (300) when the downward movement of theplunger body (300) from the first location to the second location iscompleted.

The return prevention hook (161) is configured to be interlocked withthe interlocking body (340) by elastic restoring force in the operationof be interlocked with the interlocking body (340). Specifically, thereturn prevention hook (161) may be configured to have a structurecomprising a rotatable body (1611) elastically rotatably coupled arounda rotary shaft (1613) and at one side of the inner case (102), and ahook body (1612) slantly protruding from the inner side surface of therotatable body (1611) in a downward and inward direction. In thisembodiment, the rotary axis (1613) is configured to elastically supportthe rotatable body (1611) in a inward and protruding direction of thehook body (1612) by applying elastic force according to a materialcharacter of elastic material.

By this return prevention hook (161), the returning movement of theplunger body (300) to the first location after the movement from thefirst location to the second location is completed is prevented, andtherefore, the user's inserting and using another body attachable unit(20) again at the user's discretion may be prevented.

The state of the operation of the return prevention hook (161) will bedescribed in detail, and if the plunger body (300) is moved to thesecond location by the operation of the pressure button (110) in a statethat the plunger body (300) is positioned at the first location as shownin FIG. 17, the hook body (1612) is pressurized by the interlocking body(340) of the plunger body (200) during the movement of the plunger body(300) to the second location as illustrated in FIG. 18, and then thereturn prevention hook (161) is elastically rotated in a clockwisedirection (an outward direction) around the rotary axis (1613). Afterthat, if the movement of the plunger body (300) to the second locationis completed as shown in FIG. 19, the return prevention hook (161) isreturned by being elastically rotated around the rotary shaft (1613) ina count-clockwise direction (an inward direction). Likewise, as thereturn prevention hook (161) is elastically return-rotated, the lowerportion of the return prevention hook (161) is interlocked with theupper portion of the interlocking body (340) of the plunger body (300),and therefore the returning movement of the plunger body (300) to thefirst location in a state interlocking with the return prevention hook(161) and the interlocking body (340) is prevented.

Meanwhile, the applicator (10) is configured to extract and remove theneedle unit (550) of the body attachable unit (20) from the human bodyat a time of the completion of outward discharge movement of the bodyattachable unit (20) from the first location to the second location, andfor this purpose, the applicator (10) may comprise a needle extractingmeans (N) configured to upwardly move the needle unit (550) and extractand remove the needle unit (550) from the human body at a time of thecompletion of the movement of the plunger body (300) from the firstlocation to the second location.

The needle extracting means (N) may comprise a needle extracting body(400) coupled with the needle head (551) of the needle unit (550) andlinearly move along the inner case (102) from the first location to thesecond location together with the plunger body (300) by beinginterlocked with the plunger body (300), and a needle extracting elasticspring (S2) applying elastic force to the needle extracting body (400)in a direction that the needle extracting body (400) upwardly movestoward the first location.

The needle extracting body (400) is interlockedly coupled to the plungerbody (300), and for this purpose, a separate elastic hook (410)configured to be elastically transformable is provided at the needledischarge body (400), and the elastic hook (410) is elastically biasedin a direction interlockedly coupled to the hook interlocking unit (350)of the plunger body (300). Accordingly, if the plunger body (300) islinearly moved from the first location to the second location accordingto the operation of the pressure button (110), the needle extractingbody (400) is also linearly moved to the second location together withthe plunger body (300).

In this embodiment, a needle extracting pressurizing unit (130)configured to pressurize the elastic hook (410) in an inward directionso that the elastic hook (410) is released from the interlock with thehook interlocking unit (350) of the plunger body (300) according to themovement of the needle extracting body (400) to the second location isincluded in the inner case (102).

If the pressure is applied to the pressure button (110) according thestructures described above, the needle extracting body (400) linearlymoves from the first location to the second location together with theplunger body (300) as illustrated in FIG. 19, at the same time theelastic hook (410) of the needle extracting body (400) is pressurized bythe needle extracting pressurizing unit (130) and is released from thestate interlocked with the hook interlocking unit (350), and thereforethe needle extracting body (400) is upwardly return-moved toward thefirst location by the elastic force of the needle extracting elasticspring (S2) as shown in FIG. 20.

In this embodiment, because the needle extracting body (400) is coupledwith the needle head (551) of the needle unit (550) through an end of aneedle head coupling unit (420), during the operation that the needleextracting body (400) is upwardly return-moved, the needle unit (550) ismoved together and removed from the human body. The needle head couplingunit (420) is formed at the lower end portion of the needle extractingbody (400) by a form of being interlockedly coupled to the couplinggroove (552) formed at the needle head (551).

Meanwhile, according to the movement of the plunger body (300) to thesecond location by the elastic force of the plunger elastic spring (S1)the sensor probe (521) and the needle unit (550) of the body attachableunit (20) is inserted into the human body, but the needle unit (550) maybe slightly retracted in a direction opposite to a human body insertiondirection by reaction force generated by insertion resistance during theprocess of inserting the needle unit (550) to the human body. In thiscase, because the sensor probe (521) is not inserted into the human bodyto a proper depth, the retraction of the needle unit (550) needs to beprevented. For this, a needle supporting block may be coupled to theneedle attachable body (400), and the needle supporting block isconfigured to downwardly support an upper end of the needle unit (550)so that the needle unit (550) cannot be upwardly moved with respect tothe needle extracting body (400).

Next, use states of the assembly of the sensor applicator describedabove will be described with respect to FIGS. 21 to 25.

FIGS. 21 to 25 are views illustrating use states of a continuous bloodglucose measurement apparatus according to operation order step by stepaccording to an embodiment of the present disclosure.

First, as illustrated in FIG. 21, the protection cap (200) of theapplicator (10) is separated. In the operation of separating theprotection cap (200), the release paper (561) of the adhesive tape (560)of the body attachable unit (20) is separated together with theprotection cap (200) and removed from the adhesive tape (560). Afterthat, the sensor applicator assembly is located on a position of thehuman body to attach the body attachable unit (20), and in this state,after changing a mode of the pressure button (110) from the safe mode tothe pressurization standby mode, the pressure button (110) is operatedto be pressurized.

If the pressurizing operation is performed to the pressure button (110),the state interlocking with the plunger body (300) is released by themovement of the shooting plate (150), therefore the plunger body (300)is downwardly moved in a direction outwardly discharged by the plungerelastic spring (S1) as illustrated in FIGS. 22 and 23, and in thisprocess, the needle unit (550) and the sensor probe (521) of the bodyattachable unit (20) is inserted into the human body (E). In this time,the body attachable unit (20) is adhered to a surface of the human body(E) by the bottom surface of the adhesive tape (560). Likewise, if theplunger body (300) is moved in an outwardly discharged direction, theplunger body (300) is interlocked by the return prevention hook (161) ofthe inner case (102) and therefore the plunger body (300) cannotupwardly move again as illustrated in FIG. 23. Accordingly, anapplicator (10) which is already used cannot be reused again.

Meanwhile, according to an embodiment of the present disclosure, asillustrated in FIG. 22, in a state that the plunger body (300) is movedto the second location which is an outwardly discharging direction, theplunger body (300) and a lower surface of the body attachable unit (20)to which the plunger body (300) is coupled are formed to have the sameheight as the lower surface of the main case (100). However, asillustrated in the enlarged view of FIG. 22, the lower surface of theplunger body (300) may further downwardly protrude than the lowersurface of the main case (100) by a distance X, and therefore the lowersurface of the body attachable unit (20) coupled to the plunger body(300) also further protrudes than the lower surface of the main case(100) by the distance X.

Like this, the plunger body (300) is configured to further protrude fromthe opening of the main case (100) during the elastic movement of theplunger body (300), and therefore the body attachable unit (20) coupledto the plunger body (300) may be firmly attached to the surface of thehuman body, and specially, even when the user slightly moves the maincase (100) upwardly because of fear during the process that the useroperates the applicator, the body attachable unit (20) may be stablypressurized and contacted to the surface of the human body because theplunger body (300) further protrudes than the opening of the main case(100).

If the plunger body (300) is downwardly moved, the sensor fixing hook(330) of the sensor receiving unit (301) can be received from a stateinterlockedly coupled with the body attachable unit (20) as illustratedin FIG. 23. Additionally, the elastic hook (410) of the needleextracting body (400) is pressurized in an inward direction by theneedle extracting pressurizing unit (130) of the inner case (102) andthe state interlocked with the plunger body (300) is released.

Accordingly, if the plunger body (300) is downwardly moved, at the sametime the needle extracting body (400) is upwardly return-moved by theneedle extracting elastic spring (S2) as illustrated in FIG. 24. In thistime, because the needle unit (550) is upwardly moved together with theneedle extracting body (400), the needle unit (550) is extracted andremoved from the human body (E).

In this state, because the interlock between the sensor fixing hook(330) and the body attachable unit (20) is releasable as describedabove, the applicator (10) can be upwardly separated and removed asshown in FIG. 25, and if the applicator (10) is separated and removed inthis way, only the body attachable unit remains in the state attached tothe human body (E).

After that, the sensor unit (520) and the wireless communication chip(540) of the body attachable unit (20) can initiate operation by theoperation of a pressurizing operation module (570) of the bodyattachable unit (20) and so on, and therefore the measurement result ofthe blood glucose by the body attachable unit (20) can be transmitted toa separate external terminal According to an embodiment of the presentdisclosure, because both of the sensor unit (520) and the wirelesscommunication chip (540) are installed to the body attachable unit (20),no additional work for connecting and coupling a separate transmitter isneeded.

Next, details of the body attachable unit (20) will be describedaccording to an embodiment of the present disclosure.

FIG. 26 is a perspective view conceptually illustrating an outerstructure of a body attachable unit attached to a human body accordingto an embodiment of the present disclosure, FIG. 27 is an explodedperspective view conceptually illustrating components of a bodyattachable unit, FIG. 28 is a cross-sectional view taken along line“C-C” of FIG. 26, FIG. 29 is a cross-sectional view taken along line“D-D” of FIG. 26, and FIG. 30 is a conceptual view illustrating aoperation state of a pressurizing operation module according to anembodiment of the present disclosure.

The body attachable unit (20) according to an embodiment of the presentdisclosure is configured to comprise the housing (510) to which theadhesive tape (560) is attached so that a bottom side of the housing(510) can be attached to skin, the sensor unit (520) disposed inside thehousing (510) so that one end portion of the sensor unit (520)externally protrudes from the bottom side of the housing (10) and isinserted into the human body when the housing (510) is attached to theskin, and a PCB board (530) arranged inside the housing 510).

One end portion of the sensor unit (520) is formed to be inserted intothe human body and the other end portion of the sensor unit (520) isformed to contact the PCB board (530), a sensor body unit (522) isformed at the other end of the sensor unit (520) to be contacted with anelectrical contact point of the PCB board (530), and a sensor probe unit(521) is formed at the one end portion and the sensor probe unit (521)is formed to extend in the form of being bent from one side of thesensor body unit (522) and outwardly protrudes from the housing (510)and is inserted into the human body. The sensor body unit (522) isformed to have a structure with a relatively large area, and the sensorprobe unit (521) is formed to have a relatively narrow and longstructure.

The housing (510) may be formed to be divided into a upper housing (512)and a lower housing (511) to form an inner accommodating space, a sensorsupporting unit (5121) supporting the sensor body unit (522) to bespaced apart from the electrical contact point (531) of the PCB board(530) at a certain distance is formed inside the housing (510), and asensor guide unit (not shown) configured to support and guide a certainsection of the sensor probe unit (521) is also formed inside the housing(510). Additionally, a board supporting unit (5113) for fixedlysupporting the PCB board (530) at a certain location may be also formedinside the housing (510).

The electrical contact point (531) is formed at the PCB board (530) tobe electrically connected with the sensor unit (520), and the wirelesscommunication chip (540) is installed to the PCB board (530) to transmitthe glucose measurement result measured by the sensor unit (520) to anexternal terminal. According to an embodiment of the present disclosure,by installing the wireless communication chip (540) at the inside of thebody attachable unit (20), the communication with the external terminalcan be easily performed without a work connecting a separatetransmitter.

Further, a battery (535) configured to supply power to the PCB board(530) is installed at the inside of the housing (510), and the battery(535) is not installed at one side of the PCB board (530) but disposedat an area independent from the PCB board (530). Accordingly, the PCBboard (530) and the battery (535) are independently arranged so that anyarea of the PCB board (530) and the battery (535) projecting into thebottom surface of the housing (530) cannot overlap each other. Byarranging the PCB board (530) and the battery (535) to areas independentto each other, respectively, the thickness of the body attachable unit(20) may be reduced and the size of the body attachable unit (20) may bemore minimized. In this embodiment, at the PCB board (530), a separatecontact terminal (532) may be formed to extend to the battery (535) tobe electrically contacted and connected to the battery (535).

The body attachable unit (20) according to an embodiment of the presentdisclosure is formed so that the other end portion of the sensor unit(520), i.e., the sensor body unit (522), is contacted to the electricalcontact point (531) of the PCB board (530) by the manipulation oroperation of the user, and according to this electrical contact, theoperation of the body attachable unit (20) may be initiated.Accordingly, the embodiment of the present embodiment is configured toperform the power supply as well as the initiation of the operation ofthe sensor unit (520), the wireless communication chip (540) and othercomponents by the electrical connection of the sensor unit (520) and thePCB board (530) by the manipulation of the user.

The housing (510) may have a separate pressurizing operation module(570) activated by the operation of the user to connect the other endportion of the sensor unit (520) and the electrical contact point (531)of the PCB board (530) by the operation of the user.

The pressurizing operation module (570) is movably connected to thehousing (510) and may comprise a movable pressurizing body (571)configured to be movable in a pressurizing direction by the pressureapplied by the user, and according to the movement of the movablepressurizing body (571) at least a partial area of the other end portionof the sensor unit (520) is transformed by the pressure of the movablepressurizing body (571) and contacted to the electrical contact point(531) of the PCB board (530).

Additionally, the pressurizing operation module (570) may furthercomprises a button cover (572) having flexible material and a structurecovering an outer surface of the movable pressurizing body (571) andcoupled to the housing (510) so that the button cover (572) can beexposed to the outside of the body attachable unit (20) in order to becapable of the pressurizing operation by the user, and the couplingportion between the button cover (572) and the housing (510) may beprocessed to be sealed.

In this embodiment, the seal processing means at the coupling portionbetween the button cover (572) and the housing (510) may be configuredto use a double-side tape (580). For example, one side of thedouble-side tape (580) is adhered to the other portion of the sensorunit (520), such as one side of the sensor body unit (522), along itscircumferential edge, the other side of the double-side tape (580) isadhered to the inner-side surface of the button cover (572) along itscircumferential edge, and this double-side tape (580) can seal thecircumferential edge of the button cover (572). In this embodiment, thedouble-side tape (580) may be adhered to the other side of the sensorbody unit (522) along the circumferential edge as well, and by this, thesensor body unit (522) may be adhered and fixed to the sensor supportingunit (5121) along the circumferential edge of the sensor body unit (522)by using the double-side tape (580).

In a state that the circumferential edge of the sensor body (522) isadhered and fixed to the sensor supporting unit (5121) by thedouble-side tape (580), the center section of the sensor body unit (522)is transformed by the pressure of the movable pressurizing body (571)and may contact the electrical contact point of the PCB board (530) asillustrated in FIG. 30. Although the movable pressurizing body (571) ismoved in the pressurized direction, because the button cover (572) ismade of flexible material and the circumferential edge portion of thebutton cover (572) is adhered to the housing (510) by the double-sidetape (580), only the center portion of the button cover (572) istransformed in the pressurized direction and the circumferential edgeportion of the button cover (572) is adheredly fixed and remains thesealed state.

Meanwhile, it is preferred that after the sensor body unit (522) iscontacted to the electrical contact point (531) of the PCB board (530)by the operation of the user the contact status can be stably maintainedfor stable measurement of blood glucose, and for this, the movablepressurizing body (571) is formed to be fixedly positioned in a statethat the movable pressurizing body (571) is moved in a pressurizeddirection by the urging force.

For fixing the position of the movable pressurizing body (571), aprotruding guide unit (5711) protruding along a movement direction ofthe movable pressurizing body (571) is formed at the movablepressurizing body (571) as illustrated in FIG. 31, and a locking hook(5712) may be formed at the outer circumferential surface of theprotruding guide (5711). Additionally, an interlocking projection (5124)to which the locking hook (5712) of the protruding guide unit (5711) ina state that the movable pressurizing body (571) is moved in thepressurized direction may be formed at the housing (510). The positionof the movable pressurizing body (571) may be fixed as the locking hook(5712) is interlockedly coupled to the interlocking projection (5124) asshown in FIG. 30.

In this embodiment, the interlocking projection (5124) may be formed atthe sensor supporting unit (5121) of the housing (510), at least twoguide fixing units (5123) separated to each other, formed along acircumferential direction and having a structure covering the protrudingguide unit (5711) of the movable pressurizing body (571) are formed atthe sensor supporting unit (5121) of the housing (510) as illustrated inFIG. 31, and the interlocking protrusion (5124) may be formed at eachguide fixing unit (5123). Additionally, each guide fixing unit (5123)may be arranged in a structure being elastically supported by theelastic supporting unit (5125) which is configured to be elasticallytransformable.

Accordingly, during the process that the movable pressurizing body (571)is moved toward the pressurized direction the guide fixing unit (5123)is elastically transformed and makes the movement of the movablepressurizing body (571) smooth, after the movement of the movablepressuring body (571) is completed, the guide fixing unit (5123) iselastically returned and the locking hook (5712) is interlockedlycoupled to the interlocking projection (5124), and because the guidefixing unit (5123) is elastically supported by the elastic supportingunit (5125), the interlocking coupling state between the locking hook(5712) and the interlocking projection (5124) is stably maintained.

Meanwhile, the sensor unit (520) may consist of the sensor body unit(522) and the sensor probe unit (521) as described above, and a pressuretransforming unit (523) configured to be transformed by the pressurizingmovement of the movable pressurizing body (571) and contacted to theelectric contact point (531) of the PCB board (530) may be formed at thesensor body unit (522).

The pressure transforming unit (523) comprise a first cut area (5231)having a structure cut along a first cut line (5232) formed at thecenter section of the sensor body unit (522) as illustrated in FIG. 32,and the first cut area (5231) may be formed to be transformable by thepressure applied by the movable pressurizing body (571).

Additionally, the pressure transforming unit (523) further comprise asecond cut section (5233) positioned at the center section of the sensorbody unit (522) and having a structure cut along a second cut line(5234) formed at the outer section of the first cut line (5232), and thefirst cut area (5231) and the second cut area (5233) may be formed to betransformable by the pressure applied by the movable pressurizing body(571).

In this embodiment, the first cut line (5232) is formed as an partiallyopened structure in a closed loop, and the second cut line (5234) isformed to have an opened section at the position opposing to the openedsection of the first cut line (5232) and formed in a closed-loopstructure surrounding the opened section of the first cut line (5232).

If the movable pressurizing body (571) is operated by the pressureaccording to the structure described above, a first cut section (5231)of the pressure transforming unit (523) is downwardly elasticallytransformed as illustrated in FIGS. 33 (a) and (b), then a second cutsection (5233) formed at an outer section of the first cut are (5231) isdownwardly elastically transformed sequentially, and therefore becausethe first cut section (5231) directly contacting the electric contactpoint (531) of the PCB board (530) contact the electric contact point(531) of the PCB board (530) in a relatively horizontal state, thecontacting state to the electric contact point (531) of the sensor bodyunit (522) can be more stably maintained.

Meanwhile, at the PCB board (530), a plurality of electric contactpoints (531) electrically contacting the sensor body unit (522) mayprotrude toward the sensor body unit (522), and the protruding height ofat least one of the plurality of electric contact points (531) may behigher than the rest.

For example, when two electric contact points (531) are formed on thePCB board (530) as illustrated in FIG. 34, the protruding height of oneof the electric contact points (531) is formed be higher than the otherof the electric contact points (531), and therefore clearance distancesd1, d2 are formed differently from each other.

By this arrangement structure, the contact of the sensor body unit (522)to the electric contact point (531) even without the pressure operationof the user due to the manufacture and assembly tolerance may beprevented.

Specifically, according to an embodiment of the present disclosure, inthe housing (510), the sensor body unit (522) of the senor unit (520)and the electric contact point (531) of the PCB board are disposed to beseparated from each other, but can contact each other by the pressureoperation of the user. However, because the housing (531) may be formedin a very thin structure, it may be difficult of stably maintaining theseparation state between the sensor body unit (522) and the electriccontact point (531) in the housing (510). Specially, the sensor bodyunit (522) and the electric contact point (531) may be manufactured anddistributed to customers in a state that the sensor body unit (522) andthe electric contact point (531) contact each other by the manufactureand assembly tolerance and other reasons before the pressure operationof the user.

If the protruding height of at least one of the plurality of electriccontact points (531) is higher that the rest of the electric contactpoints (531) as described above, only the electric contact point (531)having the highest protruding height may contact the sensor body unit(522) and the other electric contact points (531) may maintain aseparation state from the sensor body nit (522). This is because thehighest protruding contact point (531) can perform the function ofupwardly supporting the sensor body unit (522). In this embodiment, theplurality of electric contact points (531) may be configured toelastically transformable and be formed to elastically protruding fromthe PCB board (530), and such an elastic force may perform the desiredfunction of support and contact associated with the sensor body unit(522).

Even if the sensor body unit (522) and at least one of the electriccontact points (531) contact each other but only one of the electriccontact points (531) contacts the sensor body unit (522), the operationof the body attachable unit (20) is not initiated. Accordingly, theoperation of the sensor unit (520), the wireless communication chip(540), and other components is not initiated, and the power supply bythe battery (535) may not be initiated.

This operation initiation prevention function can result from simplemeans for setting the circuit pattern of the PCB board (530) to beactivated only when all of the plurality of the electric contact points(531) contact the sensor body unit (522).

When the plurality of electric contact points (531) have differentprotruding heights from each other, the pressurizing operation module(570) may need to be formed so that the movement distance of the movablepressurizing body (571) can be greater than the separation distancebetween the lowest protruding electric contact point (531) among theplurality of the electric contact points (531) and the sensor body unit(522).

Although embodiments of configuration of the pressurizing operationmodule (570) operated by the pressure type with respect to the structureof contacting the sensor body unit (522) and the electric contact point(531) by the user's operation are described above, various types inaddition to the pressure type may be implemented, and some exemplaryconfigurations are described as follows.

FIGS. 35 to 37 are conceptual views of various configuration of acontact point connection module according to embodiments of the presentdisclosure.

A contact point connection module (590) which is operated by themanipulation of the user so that the sensor body unit (522) and theelectric contact point (531) of the PCB board (530) contact each otheris illustrated in FIGS. 35 to 37, and this contact point connectionmodule (590) may be configured to operate in a type that in a state thatthe contact point connection module (590) is positioned between thesensor body unit (522) and the electric contact point (531) of the PCBboard (530) to block their contact the contact point connection module(590) may be moved by the operation of the user to release from blockingthe contact between the sensor body unit (522) and the electric contactpoint (531) of the PCB board (530).

Specifically, the electric contact point (531) of the PCB board (530) isformed to elastically protrude in a direction that the electric contactpoint (531) can contact the sensor body unit (522), and as the contactpoint connection module (590) releases from blocking the contact betweenthe sensor body unit (522) and the electric contact point (531) of thePCB board (530), the electric contact point (531) of the PCB board (530)is configured to be elastically moved by the elastic force and becontacted to the other end portion of the sensor unit (520).

In this embodiment, the contact point connection module (590) may beconfigured to comprise a movable plate (591) disposed between the sensorbody unit (522) and the electric contact point (531) of the PCB board(530) and installed to be movable according to the operation of the userinside the housing as illustrated in FIG. 35.

As shown in FIG. 35(a), in the assembled state that the movable plate(591) is inserted into the inside of the housing (510), the movableplate (591) is positioned between the sensor body unit (522) and theelectric contact point (531) to block the contact between the sensorbody unit (522) and the electric contact point (531), and as illustratedin FIG. 35(b), if the movable plate (591) is moved in a direction ofbeing extracted and removed from the housing (510) by the operation ofthe user, the electric contact point (531) is upwardly moved by theelastic force and contacted to the sensor body unit (522).

Meanwhile, as illustrated in FIG. 36, the movable plate (591) isinstalled to be movable from the first location to the second locationby the operation of the user, and a penetrating hole (593) may be formedat one side of the movable plate (591) and the penetrating hole (593) isconfigured to pressurize the electric contact point (531) toward the PCBboard (530) at the first location and release the pressurized state ofthe electric contact point (531) at the second location.

Accordingly, as shown in FIG. 36(a), in a state that the movable plate(591) is positioned at the first location inside the housing (510), thecontact between the sensor body unit (522) and the electric contactpoint (531) is blocked by the movable plate (591), and as illustrated inFIG. 36(b), if the movable plate (591) is moved to the second locationin the housing (510), the electric contact point (531) is elasticallymoved, penetrates the penetrating hole (593), and contact the sensorbody unit (522) because the penetrating hole (593) of the movable plate(591) is positioned between the electric contact point (531) and thesensor body unit (510).

In this embodiment, a stopper unit (592) formed to limit a movable rangeof the movable plate (591) to between the first location and the secondlocation may be formed at the movable plate (591).

Meanwhile, the movable plate (591) may be configured to be unable toreturn to the first location again so that the position of the movableplate (591) is fixed in a state that it is moved to the second location.

For example, a locking hook (594) is formed at one end portion of themovable plate (591), an interlocking projection (595) configured to beinterlocked with the locking hook (594) in a state that the movableplate (591) is moved to the second location is formed in the housing(510), and as the locking hook (594) is interlockedly coupled to theinterlocking projection (595), the position of the movable plate (591)is fixed to the second location.

Further, as illustrated in FIG. 37, a contact point connection unit(596) made of conductive material may be additionally installed to themovable plate (591). This may be configured in a structure that thecontact point connection unit (596) is installed to a portion where thepenetrating hole (593) of the movable plate (591) is formed, and theelectric contact point (531) and the sensor body unit (522) areelectrically connected and contacted to each other by the contact pointconnection unit (596) when the movable plate (591) is moved.

FIGS. 38 and 39 are views schematically illustrating a structure of amode change locking unit of a pressure button according to an embodimentof the present disclosure.

The pressure button (110) according to an embodiment of the presentdisclosure may be configured to be mode-changeable between a safe modepreventing a pressurizing movement of a pressurizing manipulation and apressurizing standby mode capable of performing the pressurizingmovement according to the pressurizing manipulation as described above.

In this embodiment, the pressure button (110) comprises a locking unit(115) configured to block a mode change state of the pressure button(110) and release the block of the mode change state of the pressurebutton (110).

The locking unit (115) is configured to maintain the blocking ofchanging a mode state of the pressure button (110) to the pressurizingstandby mode in the safe mode and be released from the blocking by themanipulation of the user.

The pressure button (110) is slidably movably installed to a buttonguide groove (1011) of the main case (100), and the status of the modeof the pressure button (110) is changed between the safe mode and thepressuring standby mode according to the sliding movement of thepressure button (110). Accordingly, the pressure button (110) maintainsthe safety mode in the button guide groove (1011), but the mode of thepressure button (110) may be changed to the pressurizing standby mode bythe sliding movement caused by the manipulation of the user.

In this embodiment, the locking unit (115) is configured to block themode change of the pressure button (110) in a way of limiting thesliding movement of the pressure button (110). For example, one end ofthe locking unit (115) is coupled to the pressure button (110) and theother end of the locking unit (115) is interlocked with the button guidegroove (1011) to limit the sliding the movement of the pressure button(110).

More specifically, the locking unit (115) may be configured to comprisea locking main body (1151) of which one end is coupled to the pressurebutton (110) to be operated by the user as illustrated in FIG. 38, and alocking hook (1152) formed to protrude at one side of the locking mainbody (1151) to be interlocked with the inner circumferential surface ofthe button guide groove (1011).

In this embodiment, the locking main body (1151) is rotatably coupled tothe pressure button (110), and the locking main body (1151) isconfigured to be releases from the interlock with the button guidegroove (1011) of a locking hook (1152) by the user's manipulation ofrotating the locking main body (1151). Although the rotatably movablestructure of the locking main body (1151) consists of using a hinge andthe like, the rotatably movable structure of the locking main body(1151) may be configured to be easily rotatable by the user by using acoupling unit with soft material as illustrated in FIGS. 38 and 39.

Additionally, the locking main body (1151) is formed to be elasticallytransformable, the locking main body (1151) is configured to be releasedfrom the interlock with the button guide groove (1011) of the lockinghook (1152) as the user rotates the locking main body (1151) to beelastically transformed, the locking main body (1151) is coupled to thepressure button (110) while the locking main body (1151) is separatableand removable from the pressure button (110), and the locking main body(1151) may be configured to be released from the interlock with thebutton guide groove (1011) of the locking hook (1152) as the userseparates and removes the locking main body (1151).

According to the embodiment, in the operation that the mode of thepressure button (110) is changed from the safe mode to the pressurizingstandby mode, the mode change is performed through the separate lockingunit (115), and therefore the user can more pay attention during theuser's operation of the mode change and the operation of the applicatorresulting from a malfunction or indeliberate behavior can be prevented.

Additionally, the locking unit (115) is formed so that the user canvisually identify the mode change of operation states including a stateblocking the mode change of the pressure button (110) and a statereleasing from the blocking of the mode change of the pressure button(110), and as described above, if the locking body (1151) of the lockingunit (115) is formed to extend to protrude from one side of the pressurebutton (110) and is configured in a way of being operated by rotationmanipulation, the user can easily identify the locking unit (115), theoperation state of the locking unit (115), i.e. whether the mode changeis blocked or the blocking of the mode change is released, can be easilyfigured out so that safer use can be induced.

FIGS. 40 and 41 are views schematically illustrate a structure andoperation status of a pressurizing operation module according to anotherembodiment of the present disclosure.

The pressurizing operation module (570) comprises a movable pressurizingbody (571) configured to pressurize the other end portion of the sensorunit (520) by being moved by the pressure force of the user as discussedabove, and a button cover (572) having soft material and covering anupper surface of the movable pressurizing body (571).

Because the button cover (572) made of soft material and having astructure of covering an upper surface of the movable pressurizing body(571) to be coupled to the housing (510), after the downward movement ofthe movable pressurizing body (571) according to the user's pressurizingmanipulation is completed, the shape of the button cover (572) maintainsa form of being freely transformable due to the character of softmaterial since there is no separate supporting structure. Thisembodiment looks unsightly and the user has difficulty in clearlyidentifying a state of whether the user operates to pressurize thepressurizing operation module (570) or not.

The pressurizing operation module (570) according to another embodimentof the present disclosure is configured that as the operation of thepressurizing operation module (570) is completed, a state of thepressuring operation module (570) different from a state before theoperation is initiated is fixed, specially, the user can easily visuallyidentify the state before the operation is initiated and the state afterthe operation is completed.

For this, as illustrated in FIG. 40, a pressurizing protruding portion(5713) upwardly protruding is formed on an upper surface of the movablepressurizing body (571), a button cover (572) is installed to beelastically transformable by being upwardly protruded by thepressurizing protruding portion (5713) in a state before the operationof the pressurizing operation module (570) is initiated. Accordingly, anelastically protruding unit (5721) configured to be elasticallytransformable to be upwardly protruded by the pressurizing protrudingportion (5713) of the movable pressurizing body (571) is formed at thecenter portion of the button cover (572).

As shown in FIG. 41, as the pressurizing operation module (570) isoperated to downwardly move the movable pressurizing body (571), thebutton cover (572) is released from a state directly contacting thepressurizing protruding portion and is return-transformed to a flatstate.

According to this structure, in a state that the movable pressurizingbody (571) is downwardly moved according to the operation of thepressurizing operation module (570), the upper surface of the buttoncover (572) becomes flat and the state of the button cover (572) isfixed by being elastically supported by its own elastic force.Additionally, before the pressurizing operation module (570) isoperated, the elastically protruding unit (5721) is configured toprotrude at the center portion of the button cover (572), but after thepressurizing operation module (570) is operated, the elasticallyprotruding unit (5721) is configured to be return-transformed and becomeflat, and therefore the protrusion state and the release state releasedfrom the protrusion of the elastically protruding unit (5721) appearbefore and after the operation of the pressurizing operation module(570), respectively, and due to this the before operation state and theafter operation state can be easily identified.

FIG. 42 is a view schematically illustrate a structure of a pressurizingoperation module according to still another embodiment of the presentdisclosure.

As shown in FIG. 42, the movable pressurizing body (571) and the buttoncover (572) of the pressurizing operation module (570) are formed to beintegrated into one single body.

If the movable pressurizing body (571) is downwardly moved by theoperation of the pressuring operation module as discussed above as themovable pressurizing body (571) with rigid material and the button cover(572) with soft material are independently formed, the button cover(572) may be freely transformable and there may be difficulty inmanufacturing and increasing the cost because of their separatemanufacturing processes.

To solve those issues, the movable pressurizing body (571) and thebutton cover (572) of the pressurizing operation module (570) may beformed to be integrated into one single body. In this embodiment, thepressurizing operation module (570) may be made of soft or flexiblematerial like the button cover (572) to improve maneuverability, and themovable pressurizing body (571) may be formed to be thicker to have morestiffness relatively.

In this embodiment, the movable pressurizing body (571) and the buttoncover (572) of the pressurizing operation module (570) can bemanufactured as one single piece by one single process, and it canimprove maneuverability due to the character of the soft or flexiblematerial and prevent the damages to the sensor unit (520) and othercomponents caused by interference or wear.

FIG. 43 is a perspective view of schematically illustrating detailedconfiguration of a sensor unit according to still another embodiment ofthe present disclosure.

As discussed above, the sensor unit (520) may be configured to comprisea sensor body unit (522), wherein the pressure transforming unit (523)is formed at the center area of the sensor body unit (522) to contact aelectric contact point of the PCB board, and a sensor probe unit (521)formed to be extended in a structure bent from one side of the sensorbody unit (522) to be inserted into the human body.

In this embodiment, a partial area of the pressure transforming unit(523) may be formed to have a cut structure, but the sensor unit (520)according to still another embodiment of the present disclosure has abridge unit (524) having a structure not being cut at a partial area onthe cut line of the pressure transforming unit (523).

Specifically, as described above, the pressure transforming unit (523)comprise the first cut area (5231) having a structure cut along thefirst cut line (5232) and the second cut area (5233) having a structurecut along the second cut line (5234), but the bridge unit (524) may beformed at a plurality of points of partial sections of the first cutline (5232) and the second cut line (5234).

By having the bridge unit (524) having a structure not being cut at somesections of the pressure transforming unit (523), the cut section of thepressure transforming unit (523) may be prevented from being transformedby self-weight or mishandling fault during the assembling ormanufacturing process.

Accordingly, if a portion of the pressure transforming unit (523) isformed as a cut section, the pressure transforming unit (523) may beeasily transformed due to mistake such as mishandling fault of amanufacturer, but if the pressure transforming unit (523) is transformedregardless of the operation of the user, there may be a problem that thepressure transforming unit (523) can contact the electric contact pointwithout the operation of the user. However, another embodiment of thepresent disclosure has the bridge unit (524) at some portions of the cutsection of the pressure transforming unit (523) to support the pressuretransforming unit (523) and prevent the pressure transforming unit (523)from being easily transformed, and therefore can maintain more preciseand stable operation performance.

FIG. 44 is a perspective view of a structure of a pressure transformingunit of a sensor unit according to an embodiment of the presentdisclosure.

As described above, the pressure transforming unit (523) is formed atthe sensor body unit (520) of the sensor unit (520) to have a cutstructure along a cut line.

In this embodiment, the pressure transforming unit (523) is configuredto comprise a first cut section (5231) having a structure cut along afirst cut line (5232), and a second cut section (5233) having astructure cut along a second cut line (5234) formed at the outer sectionof the first cut line (5232).

These structures are examples only, and the cut lines can be variouslychanged. For example, as illustrated in the FIG. 44(a), the first cutline (5232) and the second cut line (5234) may be formed to have acurved structure.

Additionally, as shown in FIG. 44(b), the first cut line (5232) may beformed to have a spiral structure, in this embodiment, the movablepressurizing body (571) of the pressurizing operation module (570) maypressurize the center area along the first cut line (5232) with thespiral structure, if pressurized by the movable pressurizing body (571),the first cut section (5231) is transformed along the first cut line(5232) having the spiral structure from the center area to the outerarea sequentially, and therefore it can be stably contacted to theelectric contact point of the PCB board without a second cut line or asecond cut section.

FIG. 45 is a view of showing various alternative examples of a sensorunit according to embodiments of the present disclosure, FIG. 46 is across-section view taken along line “E-E” of FIG. 45 for illustrating anelectrode layer-built structure of a sensor unit according to anembodiment of the present disclosure, and FIGS. 47 and 48 arecross-section views taken along line “E-E” of FIG. 45 for illustratingelectrode layer-built structures of a sensor unit according to otherembodiments of the present disclosure.

On end portion of the sensor unit (520) is formed to extend in onedirection to be inserted into the human body, and the other end portionof the sensor unit (520) is formed to be contactable with the electriccontact point of the PCB board.

The sensor body unit (522) is formed so that the other end portion ofthe sensor unit (520) can contact the electric contact point, and thesensor probe unit (521) is formed to extend from one side of the sensorbody unit (520) so that the one end portion of the sensor unit (520) canbe inserted into the human body.

The structure of the sensor unit (520) may be implemented in variousdifferent ways, as shown in FIG. 45(a), the sensor body (522) is formedin a flat plate shape having a relatively large area, and as illustratedin FIGS. 45(b) and (c), the sensor body (522) is formed in a long andthin structure and may has a bent structure or unbent structure at amiddle of the sensor body (522). However, the present disclosure is notlimited thereto, and the sensor unit (520) may be formed to have variousshapes.

The sensor probe unit (521) of the sensor unit (520) is formed to havemultiple electrode layers so that the sensor probe unit (521) of thesensor unit (520) is inserted into the human body and information onvarious material from the body fluid can be measured.

Specifically, as illustrated in FIG. 46, the sensor unit (520) may beconfigured to comprise a substrate (5201) of which one end portionextends in one direction to be inserted into the human body, a firstelectrode layer (5202) formed to be stacked on an upper surface of theone end portion of the substrate (5201), a first insulation layer (5203)formed to be stacked to cover an upper surface of the first electrodelayer (5202), a second electrode layer (5204) formed to be stacked on anupper surface of the first insulation layer (5203), and a secondinsulation layer (5205) formed to be stacked to cover an upper surfaceof the second electrode layer (5204).

According to the layering processes of the electrode layers, asillustrated in FIG. 46(a), the first electrode layer (5202), the firstinsulation layer (5203), the second electrode layer (5204) and thesecond insulation layer (5205) are stacked in order on the upper surfaceof the substrate (5201). Those electrode layers and insulation layersare formed fully or partially along the longitudinal direction of thesensor probe unit (521), and formed fully along the width direction ofthe senor probe unit perpendicular to the longitudinal direction. In thestates that the electrode layers and insulation layers are stacked, bothlongitudinal direction side surfaces are finished by being cut along thecut lines illustrated with the dotted lines in FIG. 46(a). By thiscutting process, both longitudinal direction side surfaces of the sensorprobe unit (521) can be formed to have a smooth side surface as shown inFIG. 46(b).

However, in the actual manufacturing process, there is a problem in thatthe first electrode layer (5202) and the second electrode layer (5204)may contact each other and be electrically connected with each other dueto being flowed out by a cutting blade during the process of cuttingboth longitudinal direction side surfaces. Specifically, because theelectrode layers and the insulation layers are formed with minutethickness of micro unit, those problems can be occurred. The firstelectrode layer (5202) and the second electrode layer (5204) must becompletely separated by the first insulation layer (5203) disposedtherebetween for performing normal sensor function, but if the firstelectrode layer (5202) and the second electrode layer (5204) arecontacted with each other during the side surface cutting process, itwill be classified as a defective product because the sensor functioncannot be properly performed.

To prevent this problem, an embodiment of the present disclosure mayhave a layered structure as illustrated in FIG. 47. Accordingly, one ofthe first electrode layer (5202) and the second electrode layer (5204)is exposed at one side surface of both longitudinal direction sidesurfaces of the sensor probe unit (521) and the other of the firstelectrode layer (5202) and the second electrode layer (5204) is exposedat the other side surface of both longitudinal direction side surfacesof the sensor probe unit (521) so that the first electrode layer (5202)and the second electrode layer (5204) are disposed to be exposed inopposite directions to each other.

In an example of the layering process, as illustrated in FIG. 47(a), thefirst electrode layer (5202) is stacked on the upper surface of thesubstrate (5201) to be sided toward the left side in the longitudinaldirection, the first insulation layer (5203) is stacked on the substrate(5201) and the first electrode layer (5202) to cover the upper and sidesurfaces of the first electrode layer (5202). The second electrode layer(5204) is stacked on the upper surface of the first insulation layer(5203) to be sided toward the right side of the substrate (5201) in thelongitudinal direction. The second insulation layer (5205) is stacked onthe first insulation layer (5203) and the second electrode layer (5204)to cover the upper and side surfaces of the second electrode layer(5204).

In the states that the electrode layers and insulation layers arestacked, both longitudinal direction side surfaces are finished by beingcut along the cut lines illustrated with the dotted lines in FIG. 47(a).By this cutting process, both longitudinal direction side surfaces ofthe sensor probe unit (521) may have one side surface to which the firstelectrode layer (5202) is exposed and the outer side surface to whichthe second electrode layer (5204) is exposed.

In this embodiment, unlike the layered structure illustrated in FIG. 46,the layered structure shown in FIG. 47 is stacked to be disposed inopposite directions to each other, and therefore even if the firstelectrode layer (5202) and the second electrode layer (5204) are flowedout by the cutting blade, the first electrode layer (5202) and thesecond electrode layer (5204) will not contact each other and the rateof defective products may be significantly decreased.

Meanwhile, as illustrated in FIG. 48, a third electrode layer (5206) maybe formed on a lower surface of one end portion of the substrate (5201)as a separate layer, and a third insulation layer (5207) may be formedto be stacked at the substrate (5201) and the third electrode layer(5206) to cover a lower surface of the third electrode layer (5206).Unlike the first and second electrode layers (5202, 5204), the thirdelectrode layer (5206) is formed to be stacked on the lower surface ofthe substrate (5201), therefore during the process of cutting both sidesurfaces the case of contacting the first and second electrode layers(5202, 5204) with the third electrode layer (5206) may not be occurred,and accordingly the third electrode layer (5206) may be formed on aentire lower surface of the substrate (5201) in the longitudinaldirection or on only a center portion of the lower surface of thesubstrate (5201) as illustrated in FIG. 48.

If two electrode layers are stacked sequentially on the lower surface ofthe substrate (5201), they can be stacked in opposite directions to eachother like the first electrode layer (5202) and the second electrodelayer (5204).

If two electrode layers are stacked at the sensor unit, one of twoelectrode layers is configured as an operation electrode and the otherof two electrode layers is configured as a counter electrode, and ifthree electrode layers are stacked at the sensor unit, three electrodelayers are configured as an operation electrode, a counter electrode,and a reference electrode, respectively. Additionally, more than threeelectrode layers may be formed, and each electrode layers may be usedfor measuring different material.

Additionally, the first electrode layer (5202) and the second electrodelayer (5204) are formed at an entire longitudinal direction area of thesensor probe unit (521) of the sensor unit, and are formed to extend tothe sensor body unit (522) to contact the electrical contact points ofthe PCB board.

The foregoing descriptions have been presented in order to explaincertain principles of the present disclosure by way of example, and aperson having ordinary skill in the art which the present disclosurerelates could make various modifications and variations withoutdeparting from the essential features of the present disclosure.Accordingly, the foregoing embodiments disclosed in the presentdisclosure shall be interpreted as being illustrative, while not beinglimitative, of the principle and scope of the present disclosure. Itshould be understood that the scope of the present disclosure shall bedefined by the Claims and all of their equivalents fall within the scopeof the present disclosure.

What is claimed is:
 1. An applicator for continuous glucose measurement,the applicator, in which a body attachable unit is coupled, configuredto outwardly discharge the body attachable unit by manipulation of auser to insertingly attach the body attachable unit to a body, theapplicator comprising: a main case having an inner space and an openside, wherein a pressure button is installed at one side of the maincase to be manipulated by the user; and a plunger body disposed in afirst location inside the main case and configured to be linearlymovable to a second location in an outward discharge direction accordingto manipulation of the pressure button, wherein the body attachable unitcoupled to the plunger body is movable from the first location to thesecond location together with the plunger body, the pressure button isinstalled to be mode-changeable between a safe mode, in whichpressurizing movement by pressurizing manipulation is prevented, and apressure standby mode, in which the pressurizing movement by thepressurizing manipulation is allowed, and the pressure button comprisesa locking unit configured to block a mode change from the safe mode tothe pressure standby mode, and release from block of the mode change bythe manipulation of the user.
 2. The applicator for the continuousglucose measurement of claim 1, wherein the locking unit is configuredthat a state of blocking the mode change and a state of releasing fromthe block of the mode change are visually identifiable.
 3. Theapplicator for the continuous glucose measurement of claim 2, whereinthe pressure button is configured to be mode-changed from the safe modeto the pressure standby mode by being slidably moved along an outersurface of the main case, and the locking unit is configured to blockthe mode change of the pressure button by limiting sliding movement ofthe pressure button.
 4. The applicator for the continuous glucosemeasurement of claim 3, wherein the main case comprises: an outer casecomprising a button guide groove slidably movably coupled with thepressure button and formed at one side of the outer case; and an innercase coupled to an inside of the outer case, the inner case configuredto guide a linear movement path of the plunger body, wherein one end ofthe locking unit is coupled to the pressure button and an other end ofthe locking unit is interlocked with the button guide groove to limitthe sliding movement of the pressure button.
 5. The applicator for thecontinuous glucose measurement of claim 4, wherein the locking unitcomprises: a locking main body of which one end is coupled to thepressure button to be manipulated by the user, and a locking hookprotruding at one side of the locking main body to be interlocked withan inner circumferential surface of the button guide groove.
 6. Theapplicator for the continuous glucose measurement of claim 5, whereinthe locking main body of the locking unit is rotatably coupled to thepressure button, and an interlocking state of the locking hook isreleased according to the user's rotating manipulation of the lockingmain body.
 7. The applicator for the continuous glucose measurement ofclaim 5, wherein the locking main body of the locking unit is configuredto be elastically transformable, and an interlocking state of thelocking hook is released according to the manipulation of the user whichelastically transforms the locking main body.
 8. The applicator for thecontinuous glucose measurement of claim 5, wherein the locking main bodyof the locking unit is configured to be separable and removable from thepressure button, and an interlocking state of the locking hook isreleased according to the manipulation of the user which separates andremoves the locking main body.